Faculty of Science, The Chinese University of Hong Kong (CUHK) - Visualization of biological sequences, fractal methods for coding and noncoding DNA sequence distinguish and protein structural classification

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Date: 14 May 2008 (Wednesday)
Time: 2:30am - 5:30pm
Venue: Room 232, Lady Shaw Building, CUHK

Abstract: In this talk we first give a short introduction of the fractal theory, then give some graphic and numerical representation of DNA sequences and protein sequences. These representations include DNA walk models (one-dimensional DNA walk, two-dimensional DNA walk, higher-dimensional DNA walk), chaos game representation of biological sequences and their recurrent iterated function simulation, two-dimensional portrait representation of DNA sequences (fractal dimension of the fractal set for a given tag), onedimensional measure representation of biological sequences, Z curve representation of DNA sequences, number sequence of DNA sequences. We will also talk about how to use these representations to distinguish coding and non-coding DNA sequence from the same genome, or identify the species from the fragments of the genome, and discuss protein structural classes based on their amino sequences.