Date: 17 March 2008 (Tuesday)
Time: 3:00pm - 6:00pm
Venue: Room 222, Lady Shaw Building
Abstract: This talk will cover contents or topics on modeling molecular networks and analyzing nonlinear dynamics in cellular systems in a comprehensive manner, in particular stressing on the aspects of systems and engineering. Attention will be focused on deriving general theoretical results and revealing the essential principles of biological systems based on nonlinear dynamical and control theory. Specifically, I will describe how to model or construct a general molecular network in a single cell, how to construct a molecular network with specific functions or structures, such as gene switching networks and gene oscillating networks in individual cells at the molecular level, and how to model a general multicellular system with the consideration of external fluctuations and intercellular coupling of signal biomolecules, how to design a biomolecular network from forward engineering viewpoint, and how to analyze and further control the nonlinear phenomena of living organisms at the molecula level, such as switching behaviors, cooperative dynamics or synchronization of biological oscillators in mult cellular systems.
